Dr. Muhammad Nauman Jhandier | Mukhtar A. Sheikh Hospital

Gastroenterology, Hepatology, Nutrition, General and Advanced Therapeutic Endoscopy

Board Certification

American Board of Internal Medicine Certification Gastroenterology

American Board of Internal Medicine Certification Internal Medicine

Advanced Endoscopy Fellowship Training/Junior GI Attending

Winthrop University Hospital

Division of Gastroenterology, Hepatology & Nutrition

Mineola, New York

Gastroenterology Fellowship Training

Department of Digestive Disease, Nutrition and Hepatology

University of Illinois at Chicago (UIC),

Chicago, Illinois

Fellowship Affiliate Hospitals:

University of Illinois Medical Center, Chicago, IL

Jesse Brown VA Medical Center, Chicago, IL

Internal Medicine Residency Training, New York University

Mount Sinai (Bronx) Program, New York

James J. Peters VA Medical Center, Bronx, NY

North Central Bronx Hospital, Bronx, NY

Jacobi Medical Center, Bronx, NY

Mount Sinai Medical Center, NY, NY

Research Experience

University of Illinois at Chicago (UIC)

Yale School of Medicine

Medical Education

King Edward Medical College, Pakistan

Licensures

Maine Medical License

New York State Medical License

Illinois State Medical License

Illinois Controlled Substance License

DEA Number

Pakistan Medical & Dental Council

1. Esophageal disorders: Gastroesophageal reflux disease, Esophageal stricture, Achalasia, esophageal cancer, Esophageal motility disorders, Esophageal varices, Esophageal Candidiasis
2. Gastric disorders: Peptic Ulcer Disease (PUD), H pylori, Gastric cancer, PEG (Percutaneous Endoscopic Gastrostomy Tube placement for feeding), Gastroparesis, Gastroenteritis, 
3. Duodenum and Small Bowel: Duodenal ulcer, Duodenitis, Duodenal Adenoma, Celiac disease, Irritable Bowel Syndrome (IBS), SIBO (Small Bowel Intestinal Overgrowth), Small bowel obstruction, Small bowel AVMs (Arterio-Venous Malformations), 
4. Liver Disorders: Hepatitis A, B and C, Liver cancer, Cholangiocarcinoma, Fatty liver disease, Alcoholic liver disease, Auto-immune Hepatitis, Rare hepatic disorders (Wilson’s disease, Alpha 1 AT Deficiency, Hemochromatosis)
5. Hepato-Biliary: Common Bile Duct Stones and malignancies
6. Pancreas: Acute and Chronic Pancreatitis, Pancreatic cyst, IPMN (Intra-Papillary Mucinous Neoplasms), Pancreatic Cancer diagnosis and treatment
7. Colon: Colon polyps, Colon Cancer, Inflammatory Bowel Disease (Crohn’s disease or Ulcerative Colitis), Collagenous colitis or Microscopic colitis
8. Consultation for abnormal Imaging (CT, Ultrasound or MRI) of GI/Liver
9. Diagnosis of Neuroendocrine tumors (Gastrinoma, VIPoma, CgA), GIST (Gastro-Intestinal Stromal Tumors)

General GI Procedures

1. Esophagogastroduodenoscopy (EGD) with Biopsy
2. EGD with Endoscopic Band Ligations (EBL)
3. PEG Tube placement for feeding
4. EGD with removal of precancerous or Stage I cancers (Esophageal, Gastric or Ampullary Adenomas)
5. Esophageal, gastric or duodenal metal stent placement for UGI malignancies
6. Colonoscopy with Biopsy, Metal Stent placement under Fluoroscopy 
7. Colonoscopy with removal of polyps, early cancer resection by Endoscopic Mucosal Resection
8. Treatment of hemorrhoids by band ligation
9. PEG (Percutaneous Endoscopic Gastrostomy) tube placements for advanced head/neck/pharyngeal cancers)

Advanced Therapeutic Endoscopic Procedures

1. ERCP (Endoscopic Retrograde cholangiopancreatography) for removal of bile duct stones, treatment of structures of bile duct
2. ERCP with plastic or metal stent placement for treatment of Obstructive Jaundice due to Pancreatic Cancer/ampullary carcinoma
3. EUS and EUS-FNA: Endoscopic Ultrasound and Fine Needle Aspiration for diagnosis of Gastric lesions, mediastinal lymph nodes, and pancreatic cancer diagnosis
4. Spyglass: Cholangioscopy for bile duct/Cholangiocarcinoma diagnosis and treatment
5. Difficult bile duct stones by Electrohydraulic lithotripsy vs sphincteroplasty
6. Fiducial placements for Brachytherapy/Radiation Therapy of Esophageal, Gastric, Pancreatic and Rectal cancers
7. Cancer Staging by EUS for Surgery vs Chemotherapy vs Radiation Therapy for assisting Oncologists
8. Treatment of Non-Alcoholic Fatty Liver Disease, Hepatitis B, Hepatitis C
9. EUS guided liver biopsies for liver fibrosis staging
10. Diagnosis of Liver Cancer
11. Treatment of post anastomotic biliary strictures post liver transplant 

Advanced Gastroenterologist

1. Slocum Dickson Medical Group
2. Eastern Maine Medical Center Bangor, ME

• Assistant Professor of Medicine
• Director of Therapeutic Endoscopy
• Division of Gastroenterology & Hepatology
• Albany Medical Center, Albany, NY

Present and Past Hospital’s Experience in the United States

1. Bronx VA Medical Center, Bronx, New York
2. North Central Bronx Hospital, Bronx, New York
3. Jacobi Medical Center, Bronx, NY
4. Mount Sinai Medical Center, New York, NY
5. University of Illinois Hospital, Chicago, Illinois
6. Jesse Brown VA Medical Center, Chicago, Illinois
7. Milwaukee VA Medical Center, Milwaukee, Wisconsin
8. Palos Community Hospital, Palos Heights, Illinois
9. Winthrop University Hospital, Mineola, Long Island
10. Albany Medical Center, Albany, New York
11. Eastern Maine Medical Center, Bangor, Maine
12. Saint Luke’s Hospital, New Hartford, New York
13. Saint Joseph’s Hospital, Syracuse, New York

Certificate of Excellence from Mount Sinai School of Medicine

(Bronx) Residency Program in Internal Medicine

1. American Society for Gastrointestinal Endoscopy (ASGE)
2. American College of Gastroenterology (ACG)
3. American Gastroenterological Association (AGA)
4. New York Society for Gastrointestinal Endoscopy (NYSGE)
5. Member Practice Guidelines Committee American Association for Study of Liver Disease (AASLD)

Peer Reviewed Journal Articles/Abstracts

Lactobacillus acidophilus attenuates downregulation of DRA function and expression in inflammatory models

Singh V, Kumar A, Raheja G, Anbazhagan AN, Priyamvada S, Saksena S, Jhandier MN, Gill RK, Alrefai WA, Borthakur A, Dudeja PK

Muhammad N. Jhandier, Varsha Singh, Geetu Raheja, Arivarasu Natarajan Anbazhagan, Jaleh Malakooti, Waddah A. Alrefai, Ravinder K. Gill, Pradeep K. Dudeja. Spermidine Upregulates the Function and Expression of Sodium-Hydrogen Exchanger 3 (SLC9A3) in Caco2 cells DDW 2012 (accepted for oral presentation)

Varsha Singh, Geetu Raheja, Muhammad N. Jhandier, Redouane

Boumendjel, Alip Borthakur, Seema Saksena, Ravinder K. Gill, Waddah A. Alrefai, Krishnamurthy Ramaswamy, Pradeep K. Dudeja. Up- Regulation of Intestinal Cl-/HCO3- Exchanger SLC26A3 Expression by Lactobacillus Species in CACO-2

Cells and Mouse Intestine DDW 2010

Geetu Raheja, Varsha Singh, Muhammad N. Jhandier, Jaleh

Malakooti, Redouane Boumendjel, Alip Borthakur, Ravinder K. Gill,

Waddah A. Alrefai, Krishnamurthy Ramaswamy, Pradeep K.

Dudeja.

Sodium-Hydrogen Exchanger 3 (Slc9a3) Expression Is Increased

by Lactobacillus Species Both in In Vitro and In Vivo Models DDW 2010

JhandierMN, KruglovEA, DranoffJA. Portal fibroblasts regulate bile ductular proliferation via expression of NTPDASE2. Gastroenterology. 2004, Apr; 126(S2):144. Pub Status: Published.

JhandierMN, KruglovEA, DranoffJA. Portal fibroblasts attenuate proliferation of bile duct epithelia through blockade of purinergic stimulation of MAP kinases. Hepatology. 2003, Oct; 38(S1):686A. Pub Status: Published.

JhandierMN, KruglovEA, LavoieEG, SévignyJ, Dranoff JA. Portal fibroblasts regulate the proliferation of bile duct epithelia via expression of NTPDase2. Journal of Biological Chemistry (JBC). 2005, Jun;

280(24):2986-92. Cited in PubMed; PMID: 15799977. Pub Status: Published.

JhandierMN, LiMo,M, WatanabeA, HashmiAZ, FlavellR, MehalWZ. The Phosphatidylserine Receptor (PSR) is Required for Efficient Removal of Apoptotic Cells From Injured Livers in Mice. Gastroenterology. 2007, Apr; 132(4):A830-A831. Pub Status: Published.

JhandierN, HakimW, and MehalW. Bone Marrow Derived Cells

Can Produce Leptin and Reconstitute Liver Fibrosis in Leptin

Deficient ob/ob Mice. Hepatology. 2005, Oct; 42(S1):600A-

601A. Pub Status: Published.

JhandierN, KuniyasuY, HakimW, MehalWZ. In-Vivo Antagonism

of Intrahepatic CD8+ T Cells by Altered

Peptide Ligands (APL) in Mice. Hepatology. 2006, Oct;

44(S1):672A. Pub Status: Published.

KruglovEA, ToureJ, JhandierMN, JainD, SevignyJ,

RobsonSC, DranoffJA. The ecto-nucleotidase NTPDASE2 is

selectively down-regulated in biliary fibrosis. Hepatology.

2003, Oct; 38(S1):341A. Pub Status: Published.

KuniyasuY, QamarA, SheikhSZ, JhandierMN, HakimW,

MehalWZ. Blocking intrahepatic deletion of activated CD8 (+) T cells by an altered peptide ligand. Cellular Immunology. 2005, Nov; 238(1):31-7. Cited in PubMed; PMID: 16445896. Pub Status: Published.

QamarA, SheikhSZ, MasudA, JhandierMN, InayatIB, HakimW, MehalWZ. In vitro and in vivo protection of stellate cells from apoptosis by leptin.. Digestive Diseases and Sciences. 2006, Oct; 51(10):1697-705. Cited in PubMed; PMID: 16957995. Pub Status: Published.

QamarAA, SheikhSZ, JhandierMN, MehalWZ. Leptin does not protect hepatic stellate cells from the mitochondrial pathway of apoptosis mediated by ultraviolet irradiation. Hepatology. 2004, Oct;

40(S1):614A. Pub Status: Published.

SheikhSZ, QamarAA, MasudA, JhandierMN, MehalWZ. The long isoform of the leptin receptor (OBRB) is required for the thioacetamide induced liver fibrosis in mice. Hepatology. 2004, Oct; 40(S1):536A-537A. Pub Status: Published.

WatanabeA, HashmiA, JhandierMN, GautamS, SohailMA, MahmoodS, KhanZ, MehalWZ. The Adenine receptor is present in Rat Hepatic Stellate Cells (HSC), induces HSC differentiation and inhibits HSC chemotaxis. Hepatology. 2007, Oct; 46(S1):875A. Pub Status: Published.

WatanabeA, HashmiA, JhandierMN, KhanZ, SutterwalaF, SohailMA, MahmoodS, FlavellRA, MehalWZ. HSC Express NALP3 and ASC, and Undergo Differentiation in Response to Uric Acid crystals. Hepatology. 2007, Oct; 46(S1):874A. Pub Status: Published.

Presentations/Posters

JhandierMN, KruglovEA, DranoffJA. (2003, October). Portal fibroblasts attenuate proliferation of bile duct epithelia through blockade of purinergic stimulation of MAP kinases. Poster presented at: AASLD; Boston, MA.

JhandierMN, LiMO, WatanabeA, HashmiAZ, FlavellRichard, MehalWZ. (2007, May). The Phosphatidylserine Receptor (PSR) is Required for Efficient Removal of Apoptotic Cells From Injured Livers in Mice.

Poster presented at: Digestive Diseases Weak (Accepted as a Poster of Distinction); Washington, D.C., DC.

JhandierN, KuniyasuY, HakimW, MehalWZ. (2006, October). In-Vivo Antagonism of Intrahepatic CD8+ T Cells by Altered Peptide Ligands (APL) in Mice. Poster presented at: AASLD; Boston, MA.